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The STEP 1 trial showed average weight loss of 14.9% over 68 weeks, with around half of participants losing 15% or more of their body weight

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Eli Lilly reiterated to NPR that the drugs have been "available since August." "Our current manufacturing investment of over $20 billion in the past four years is the most significant in our history, and will allow us to continue increasing capacity to safely bring these medicines to people who need them," Eli Lilly spokesperson Courtney Kasinger wrote in an email

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But some compounding pharmacies are now trying to continue this practice after a drug shortage endsskirting FDA safety regulations and oversight, and potentially jeopardizing patient health. Compounding pharmacies lower regulatory compliance costs can contribute to a lower price point, which is frequently emphasized in direct-to-consumer advertising such as a recent Super Bowl ad for compounded GLP-1s watched by 123 million people

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