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Description
Although both drug classes could theoretically offer neuroprotective benefits based on their mechanisms of action, RCTs have provided mixed or inconclusive results
Int J Clin Exp Pathol 10:13221330 Meng RD, Shelton CC, Li Y-M, Qin L-X, Notterman D, Paty PB et al (2009) -Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
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If possible, decision support tools should be used to help individuals understand the risk and benefits and assist with decision-making
& Csoka, I
