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While adjustment for contributory factors or covariates attenuated the difference in the RH group, the small sample size limited the power of the analysis and conclusions that may be drawn are therefore limited

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One study found that weekly treatment with semaglutide, a GLP-1 RA, reduced the risk of a combination of stroke, heart attack, and death from cardiovascular causes by 20% compared with placebo.

n = 1,961) and STEP 2 (NCT03552757