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Description
In both -cells and intestinal L-cells, Gcg expression is controlled by certain homeodomain proteins [94,98,100] and by cAMP-activation of protein kinase A (PKA), as demonstrated in primary rat intestinal cultures [126], isolated pancreatic cell lines [127,128] and enteroendocrine GLUTag and STC-1 cell lines [129,130]
J Endocrinol 220(2):117128

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-Lixisenatide is short-acting and might have limited CNS exposure, especially at standard doses

Timing adjustments for co-administered medications may be necessary
