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JACC Basic Transl Sci 2020;5:169-79.PubMedPMC 33

Considering Retatrutide: Side Effects and Future Availability Retatrutide's side effects share similarities with other GLP-1 agonists, including mild to moderate gastrointestinal discomfort

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What was once investigational is now reality

Studies consistently show that these medications may actually provide cardiovascular protection rather than causing harm

Retatrutide is a synthetic peptide acting as an agonist of GLP-1, GIP, and glucagon receptors (Figure 1)