does retatrutide work better than tirzepatide vs. Tirzepatide: The New Contender vs. the Current Leader Retatrutide vs Tirzepatide: Which Peptide
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Heckel B (2024) Idiopathic intracranial hypertension after Abrupt Cessation of Medication: a Case Report of Abrupt Glucagon-Like Peptide-1 (GLP-1) receptor Agonist Cessation and Review of the literature

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The Phase 2 trial tested doses from 0.5mg to 12mg, with 2mg as the standard starting dose for titration
However, this aspect of its action is potentially problematic in PWS, since many individuals with PWS already have decreased stomach emptying rates and generally slow GI transit (which does not seem to reduce their appetite)

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Retatrutide is an investigational compound not approved for human consumption