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In patients with obesity (mean age 51.3 years, 65.6% women), semaglutide compared with non-GLP-1RA anti-obesity medications was associated with lower risk for incident CUD in patients with no prior history CUD (HR: 0.56, 95% CI: 0.420.75), and recurrent CUD diagnosis in patients with a prior history CUD (HR: 0.62, 95% CI: 0.460.84)
Prospective ultrasound studies show a higher prevalence of residual gastric content in GLP-1 RA users, particularly during dose escalation or when GI symptoms are present
Beyond glucose-lowering, incretin-based therapies may provide organ protection across the cardiorenal axis
Some users have reported changes in sex drive on Ozempic
Self-administering semaglutide injections at home requires proper technique, sterile handling, and knowledge of injection sites
