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Key Clinical Evidence Phase 2 Randomized Trial in Obesity (48 weeks) Jastreboff AM et al., New England Journal of Medicine, 2023 ClinicalTrials.gov: NCT04881760 The Phase 2 study evaluated multiple doses of retatrutide versus placebo over 48 weeks

Summary of NICE guidance for GLP-1 receptor agonists and tirzepatide in adults NG28 (PDF)

10.1111/dom.13129 64
Sorli C, Harashima S-I, Tsoukas GM et al (2017) Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial

Some 8% of cancer patients considered refusing chemotherapy specifically to preserve their hair, according to one study

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