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The precaution for spironolactone in patients with diabetes mellitus is primarily due to the risk of hyperkalemia and not the risk of inducing hyperglycemia, which may occur with thiazide or loop diuretics

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Various factors and signaling pathways are linked to gut-brain axis dysfunction that putatively leads to depression (Scott et al., 2013)

Delayed gastric emptying induced by GLP-1 receptor agonists carries important clinical implications that extend beyond the intended therapeutic effects

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