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Those who have a personal or family history of thyroid cancer, certain endocrine tumors, liver or kidney conditions, or severe digestive issues should avoid it

Most events are reported as mild-to-moderate and tend to diminish over time as the body adapts

Side effect profiles differnausea, vomiting, or appetite suppression may be more pronounced with one agent

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3.7.4 Oral Retinoids Both isotretinoin and acitretin are contraindicated during pregnancy

Due to semaglutide's long half-life, thrice-weekly provides relatively modest additional benefit over twice-weekly