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Compared with non-diabetic plaques, diabetic plaques had more inflammation and oxidative stress, along with a lower sirtuin (SIRT)6 expression and less interstitial collagen content

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With a median treatment duration of 20 months, patients experienced a mean relative weight loss of 5% at 12 months, corresponding to absolute reductions of 2.8 kg at 6 months, 4.2 kg at 12 months, and 6.2 kg by the end of follow-up

Davies, V.R

At this time, GLP-1s should not be viewed as dementia treatments, but their role in long-term brain health remains an active area of research

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