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Description
Tirzepatide is the first dual agonist which has been approved for chronic weight management, but numerous other dual and/or triple agonists (cagrisema, retatrutide, mazdutide and survodutide) are also in phase 3 trials as potential treatments for obesity and its metabolic complications

Breaking the cycle requires addressing both the hormonal deficit and the excess fat simultaneously

Abstract This article examines the growing prevalence of pediatric obesity and its connection to metabolic dysfunction-associated steatotic liver disease (MASLD) in children and adolescents, focusing on the role of glucagon-like peptide-1 receptor agonists in treatment

GLP-1s One class of drugs called glucagon-like peptide-1 (GLP-1) agonists can treat both obesity, type 2 diabetes , and more

Aging models Given the close association between diabetes, aging, and neurodegeneration, GLP-1RAs have been tested in in vivo aging models

[DOI] [PubMed] [Google Scholar] 728.Pelchat M.L., Grill H.J., Rozin P., Jacobs J
