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This hinted at what higher doses might do for obesity (discussed soon)

Lipase inhibitors such as alli or Xenical (orlistat) can cause oily spotting, gas, stomach pain, fecal urgency or incontinence, soft stools, and the possibility of serious liver injury

40 Therefore, current data suggest that GLP-1 RAs do not improve exercise capacity in HFrEF

People using them for this purpose may lose more than 1015% Trusted Source PubMed Central Go to source of their body weight