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doi: 10.1016/S0140-6736(21)02188-7 [DOI] [PubMed] [Google Scholar] 194.Rosenstock J, Fras JP, Rodbard HW, et al

Rostral ventrolateral medulla: selective projections to the thoracic autonomic cell column from the region containing C1 adrenaline neurons

For maximizing weight loss, dual agonists are better

They're marketed as being cheaper, easier to use, and available to anyone, unlike prescription weight loss injections, which require a consultation and have specific eligibility criteria

Lucas, L., Russell, A., & Keast, R

Older drugs including orlistat, liraglutide and metformin do not, on this evidence, clear the bar for a meaningful reductions in weight over lifestyle change alone