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Linagliptin Added to Metformin and a Sulfonylurea The efficacy of linagliptin 5 mg added to a combination of MET and an SFU was assessed in 1058 patients with T2D in a 24-week placebo-controlled study

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Cell-type composition affects adipose gene expression associations with cardiometabolic traits

Nausea, vomiting, and diarrhea were more common in the highest 15mg dose of tirzepatide compared to lower 0.5 mg dosages of semaglutide, suggesting the latter may be a good option to minimize these side effects, although of course, with the trade-off being less weight loss, Wong, who was not involved in the study, told Medical News Today

The difference likely reflects dosing strategy: semaglutide escalates from 0.25 mg to 2.4 mg over 16 weeks, while tirzepatide escalates from 2.5 mg to 15 mg over 20 weeks
