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N Engl J Med 2017;377: 644e57

Here are some of the most common issues patients encounter: Temporary Results A 2022 study of semaglutide showed that when participants stopped treatment, they regained of their prior weight loss

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The same hormonal signaling that suppresses appetite and drives weight loss also accelerates colonic transit and increases water secretion in the lower bowel, especially during the first few weeks of treatment and after each dose increase
