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However, when the landmark trials of semaglutide (STEP 1) and tirzepatide (SURMOUNT-1) measured body composition, they found that in some analyses, around 40% of weight loss came from LBM

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) such as Ozempic, Mounjaro, and Wegovy, are a class of medications initially developed to help manage Type 2 diabetes

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(David Paul Morris/Bloomberg / Getty Images) Glucagon-like peptide-1 (GLP-1) is a hormone that impacts glucose and is regulated by GLP-1 receptors