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Description
A separate genetic strategy expressed Gqcoupled designer receptors exclusively activated by designer drugs (DREADD) under the control of the Insl5 promoter, to allow chemogenetic stimulation of colonic Lcells (Lewis et al., 2020)
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Temporary side effects such as nausea, bloating, or fatigue may occur early on but often improve as the body adjusts
However, such intervention is highly invasive, has considerable risk and is irreversible and expensive
If there are additional concerns, such as loose skin on the lower face, eyelid aging, or volume loss, Dr
Knowing how long tirzepatide takes to work helps set realistic expectations for both the benefits and the side effect adjustment period
