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June 13, 2022
Leptin participates in normal hippocampal dendritic spine formation through activation of TRPC channels in hippocampal neurons [145]
This isn't simply a matter of drinking less because you're eating lessyour brain's thirst centers are being directly influenced by the medication

GLP-1, via its receptor GLP-1R, is present in multiple brain areas, such as the hypothalamus, brainstem, and hippocampus, where it influences neuroprotection, synaptic plasticity, hunger, and cognition [29]

Injecting too shallow (intradermal) causes a painful raised welt and poor absorption

Abdominal injections typically absorb faster than thigh injections
