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More recently, encouraging clinical results from a triple-hormone-receptor agonist, Retatrutide, and several GLP-1R/GCGR dual agonists, suggest that GCGR could be a promising co-stimulating target for type 2 diabetes and obesity

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Br J Pharmacol 179(4):659676 [DOI] [PMC free article] [PubMed] [Google Scholar] Hernandez AF, Green JB, Janmohamed S, DAgostino Sr RB, Granger CB, Jones NP, et al (2018) Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

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Her urinary retention could be secondary to dysautonomia, which is common in patients with TIND