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D.AbrahamsenB.SchwartzA

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Dual-action therapy targeting both GIP and GLP-1 receptors for superior appetite suppression and enhanced metabolic results

These individual unimolecular multi-agonists activities seemed to harmonize the overall metabolic efficacy, which predominantly results from synergistic glucagon action to increase energy expenditure, GLP-1 action to reduce caloric intake and improve glucose control, and GIP action to potentiate the incretin effect and buffer against the diabetogenic effect of inherent glucagon activity

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Am J Obstet Gynecol (1995) 173(3 Pt 1):7607