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Whether that difference justifies the price increase depends on your individual response and goals

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Majumder D

One study found that patients who switched from a GLP-1 medication to phentermine were 29 percent less likely to regain all of their lost weight compared to patients who stopped GLP-1 treatment entirely without any replacement medication

Lincoff AM, Botros J, Wolski K, et al
Moreover, ICERs reports inform some step-therapy policies

In preclinical models, GLP1RAs inhibit platelet aggregation, reduce platelet activation markers, and suppress thromboxane A2 production [33]
