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In the CNS, GLP-1R is widely expressed across multiple regions implicated in energy homeostasis, reward processing, and autonomic control [16]

Those who are sensitive to medications in general often do better with a microdose approach

[1] Commonly prescribed GLP-1 agonists include semaglutide (Ozempic for diabetes, Wegovy for weight management), dulaglutide (Trulicity), liraglutide (Victoza for diabetes, Saxenda for weight management), and exenatide (Byetta, Bydureon)

Wu J, Williams GR, Branford-White C, Li H, Li Y, Zhu LM

For perimetry, we performed automated visual field testing (Humphrey Field Analyzer, Carl Zeiss Meditec, Jena, Germany) using 302 Swedish Interactive Threshold Algorithm (SITA) standard protocols, quantifying the mean deviation in decibels (dB) of all test locations compared to age-matched controls and defining abnormal perimetry as a mean deviation lower than -2 dB