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Introduction: from Adverse Events to Beneficial Events The mighty adverse event (AE) case report form (CRF) had its humble beginning in 1938 when

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After tolerating Mounjaro 10 mg weekly, the next dose is 15 mg weekly, administered 4 weeks after the last 10 mg dose

Most recently on 8 November 2023, the US Food and Drug Administration approved through an expedited process the use of tirzepatide (Zepbound®) for chronic weight management in adults with obesity, reflecting the urgent need to address gaps in obesity treatment

Studies with longer follow-up are needed to determine the durability, as weight regain after discontinuation of the medication is highly likely, and the high cost of these medications can limit their use

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