glucagon glp-1 Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and #obesity. receptor agonists and GLP-1 and glucose-dependent insulinotropic Glucagon-like peptide 1 in health

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doi: 10.1021/acs.jafc.4c12341

A safe weight-management plan should track more than weight, including: Waist size Blood pressure Blood sugar Sleep Energy Mobility Long-term disease risk When to Talk to a Primary Care Provider Patients should schedule a medical visit if weight gain continues despite lifestyle changes, or if weight gain comes with fatigue, increased thirst, snoring, joint pain, irregular periods, high blood pressure, high cholesterol, or rising blood sugar

The observed GLP-1R/GIPR dual activity is particularly similar to that of tirzepatide, a clinically approved dual incretin agonist (Jastreboff A et al., 2022)

Klein T, Augustin R, Hennige AM

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