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If the oral tablet form of ASC37 shows sufficient human PK in Phase 1 H2 2026, the category changes

This makes sense because both drugs act through GLP-1 receptor pathways, and GI effects are inherent to that mechanism

Further loss requires additional interventions while the medication works to maintain achieved results

19 The results from one study suggest that IGF-1 may lead to the induction of acne or worsen preexisting acne through upregulating inflammatory biomarkers in sebaceous genes

1 aprile 2017 [citato 5 giugno 2024];43:2S207

However, medical literature and FDA reporting databases do include chest pain and chest pressure as symptoms associated with more severe, albeit rare, adverse reactions