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Rai said the additional five years, stretching the patent from 2026 to 2031, likely stem from the Hatch-Waxman Act, a 1984 law that allows drugmakers to extend patents by up to five years to make up for time lost moving their drug through clinical trials and the FDA approval process

To determine whether the combination therapy of SGLT2is and DPP4is has a synergistic efficacy in slowing the progression of DKD, we performed chronic administration with a SGLT2i, EMPA or the combination of EMPA and a DPP4i, LINA into Spontaneously Diabetic Torii (SDT)-fatty rats, leptin receptor-mutated rats, that were given containing 0.5% NaCl (DKD rats)

Shifting fat metabolism also means individuals can witness improvements in factors such as blood lipids, which is significant for cardiovascular health

Hum Mol Genet 24 , 13901399, (2015)