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Downsides include occasional headaches during dose increases and a little more constipation than I had on tirzepatide

Miss it, and everything downstream goes wrong

These theories all come into play in some of the preclinical studies of GLP-1 RAs in animals, where it was demonstrated that GLP-1 RAs can reduce dopaminergic neuron loss and improve motor function

Can I meal plan while also on semaglutide

The extra volume may cause a slightly larger subcutaneous depot at the injection site, which can feel like a small, firm lump under the skin for a few hours
