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Aside from weight gain, the menopause transition is associated with changes in body composition including an increase in fat mass, a decrease in lean mass, and an increase in abdominal adiposity, say researchers

GLP-1 Agonists: Optimizing Therapy Across Clinical Scenarios (1.5 hours) CE/CME Course #: 25-396 Review clinical guidance on optimizing use of GLP-1 receptor agonists (RAs) for managing type 2 diabetes and weight loss, as well as their role in cardiovascular and kidney diseases

Diabetologia 49 , 21052108 (2006)

Gut microbiota modification via glucagon-like peptide-1 with beneficial neuroprotective effects

GLP-1 medications carry FDA warnings about potential risks including pancreatitis, gallbladder disease, and acute kidney injury with dehydration

A recent meta-analysis encompassing 11 observational and case-control studies across various countries revealed no statistically significant disparity in suicidal outcomes between GLP-1 RA users and those utilizing alternative antihyperglycemic medications (relative risk, 0.57