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Monitor neonates exposed to tramadol closely as neonatal opioid withdrawal can be life-threatening if not recognized and treated

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Compounded versions provide the same clinical efficacy at significantly lower cost than brand-name equivalents

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The most commonly reported side effects include: Mild nausea or upset stomach Constipation or diarrhea Fatigue Headache Reduced appetite These symptoms are usually temporary and manageable, particularly when the dose is gradually increased under supervision