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N Engl J Med 1990;322:10281031

For most patients, reaching goal weight does not signal the end of treatment but rather a transition from the weight loss phase to the weight maintenance phase, which typically requires continued pharmacological support for optimal outcomes as long as benefits outweigh risks

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Due to its immune-activating properties, it may not be suitable for chronic daily use in autoimmune patients

Iron, Vitamin B12, and Folate Supplementation Sometimes, diet alone may not be enough to maintain adequate nutrient levels

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