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These neurons innervate the amygdala (Vertes, 1991) and the hippocampus (McQuade and Sharp, 1997)

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Unlike GnRH agonists that create an artificial menopause to suppress estrogen, the weight-mediated estrogen reduction through GLP-1 agonists is more physiological
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The denominator (total users) isn't publicly available, which means you can't calculate a per-user risk from these figures

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This is a critical milestone, as even a modest reduction in body weight can lead to significant improvements in blood pressure, cholesterol, and joint pain
