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Description
The FDAs decision to ban compounded semaglutide significantly impacts patients who have relied on these unapproved versions for weight loss or diabetes management

Post-marketing surveillance and registry studies continue to accumulate real-world safety information

Similar SARs have been observed for the endogenous ligands of related class B GPCRs, including glucagon/GCGR (Unson et al., 1989) and GIP/GIPR (Hinke et al., 2001), demonstrating that interactions of peptide ligands in the 7TMD of class B GPCRs are required for receptor activation

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Pharmacol Ther 207:107473
