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As with any medication, certain individuals should avoid GLP-1 weight loss shots, including those with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or pancreatitis

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Available online at: (Accessed May 1, 2025)

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122 Two PCOS mouse models were developed using prenatal androgenization (via DHT administration to pregnant dams on gestational days 1618) and postweaning androgenization (via subcutaneous DHT implants at day 21), followed by high-fat diet exposure and 28-day treatment with GLP-1-based mono- and multi-agonists or metformin starting on postnatal day 80, with outcomes assessed at day 108