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To put it into perspective, for someone weighing 240 lbs, this translates to an average loss of 33 lbs with Semaglutide, compared to 48 lbs with tirzepatide

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The metabolic clearance occurs by proteolytic cleavage of the tirzepatide peptide backbone, -oxidation of the C20 fatty diacid moiety, and by amide hydrolysis

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Non-GLP-1 alternatives have completely different side effect profiles

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The infant's gastrointestinal tract would likely break down tirzepatide before significant absorption could occur

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Reviews in Endocrine & Metabolic Disorders, 15(3), 181

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Another significant difference between both drugs is the side effects

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