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These effects target core bioenergetic deficits that emerge early in dementia, including impaired oxidative phosphorylation, regional hypometabolism, and accumulation of reactive oxygen species

Besides, the protective and therapeutic effects of GLP-1RAs on the central nervous system have now been confirmed by several studies (25, 26)

Mace OJ, Tehan B, Marshall F (2015) Pharmacology and physiology of gastrointestinal enteroendocrine cells

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Many patients experience meaningful weight loss over time, though results vary based on individual factors and adherence to the program

Other interactions: Enhanced glucose-lowering effect: alcohol, anabolic steroids, MAOIs, testosterone