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47 Intensity: How Hard

An exploratory signal suggested a potential lower risk of heart failure hospitalization with semaglutide compared to dapagliflozin

The SURPASS-2 trial (A Study of Tirzepatide versus Semaglutide Once Weekly as an Add-On Therapy to Metformin in Participants with Type 2 Diabetes) compared the efficacy of different doses of tirzepatide with semaglutide 1 mg in patients with poorly controlled diabetes on metformin monotherapy

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A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Diabetes Care

The glucose-dependent mechanism of insulin release distinguishes GLP-1 agonists from many other antidiabetic medications, resulting in a lower risk of hypoglycemia when used as monotherapy