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More than half of the participants receiving tirzepatide lost 25% or more of their body weight during the trial period
Western blotting showed that TGF-1 + IL-1 treatment time-dependently upregulated the expression of NLRP3, ASC and active caspase-1 p20 in fibroblasts, while GSDMD-NT did not change significantly (Fig

Inflamm Bowel Dis 22:20782097

Komsuoglu Celikyurt I, Mutlu O, Ulak G, Uyar E, Bekta E, Yildiz Akar F, et al

To evaluate the safety and tolerability of LY3437943, a randomized, double-blind, placebo-controlled Phase 1 clinical trial was conducted on 45 healthy subjects

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