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It may influence GABA activity, which can have positive implications for mood stability and stress response

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Dose reductions of concurrent diabetes medications are frequently necessary when starting GLP-1s

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In anonymous complaints about Calibrate filed with the Federal Trade Commission and obtained via a Freedom of Information Act Request, one patient wrote: "I have regained half of what I originally lost, a setback representing about six months of work." Another customer said they started gaining weight back as soon as they stopped the medication cold turkey, so they got back on the medication by signing up for Calibrate's second-year program

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