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Instruct patients to promptly discontinue JANUMET and contact their physician if persistent severe abdominal pain occurs [see Warnings and Precautions (5.2)]

Perry RJ, Rabin-Court A, Song JD, et al

Studies show that after stopping GLP-1 medications, participants regain a significant portion of the weight they initially lost in some trials, about two-thirds within a year

However, severe, persistent, or unusual pain should always be assessed by a clinician

The technology combines high-intensity focused electromagnetic (HIFEM) technology with radiofrequency (RF) heat energy

Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats