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As the newest weight-loss drug on the scene, retatrutide targets three receptors: GLP-1, GIP and glucagon

Finerenone is effective at reducing cardiorenal events, but it doesnt treat diabetes

Eur J Pharmacol 2021, 911

We studied 21,538 patients with a history of hypothyroidism who were prescribed semaglutide, dulaglutide, liraglutide, or exenatide and stratified them by their weight change after starting the medication

In addition to direct actions in coronary arteries, GLP-1 RAs can prevent the formation and progression of coronary atherosclerosis through indirect mechanisms, such as maintaining glycemic control, losing weight, decreasing systolic blood pressure, obtaining beneficial effects from lipid levels, inhibiting platelet activation, reducing systemic inflammation and levels of circulating BNP (Sun et al., 2015a, 2015b