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Additionally, providers discuss realistic weight loss expectations (typically 10-15% body weight over 68 weeks in clinical trials) and common side effects including nausea, constipation, and appetite suppression

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GLP-1 agonists are used primarily to treat type 2 diabetes, but they have also been shown to be effective in weight loss and are approved by the U.S

Secara umum, terapi ini biasanya dipertimbangkan pada individu dengan: Obesitas BMI 30 kg/m Overweight dengan Penyakit Penyerta BMI 27 kg/m disertai kondisi seperti: Diabetes tipe 2 Prediabetes Hipertensi Sleep apnea Dislipidemia (kolesterol tinggi) PMOS/PCOS Fatty liver Terapi GLP-1 juga dapat dipertimbangkan pada pasien yang sudah mencoba diet dan olahraga tetapi tetap mengalami kesulitan menurunkan berat badan karena faktor hormonal dan metabolik

In recent years, the battle against obesity has seen a promising addition in the form of semaglutide, a medication initially approved for treating type 2 diabetes

Exploratory analyses from the phase 1 trial were encouraging, showing evidence of cognitive benefit for the treated group and reduced markers of neurodegeneration (Potter et al., 2021a)