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Indeed, local Ex4 infusion into the LDTg suppresses alcohol-induced locomotor stimulation, dopamine release in the NAc, memory of alcohol reward, and alcohol drinking in male rodents (Vallof et al., 2019a)

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2023 Nov 16;9(1):7

Exendin-4 The study of GLP-1R has been greatly enhanced by the discovery of the peptide agonist exendin-4 (Ex4) from the saliva of the Gila monster H suspectum (Eng et al ., 1992)

In the previously published studies, only the short-term effects of GLP-1 RA administration on urine parameters were assessed