glp-1 cirrhosis Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAs): A Pan-Steatotic Liver Disease Treatment? GLP-1 and fatty liver disease.

Description

doi: 10.1007/s40259-013-0057-y

GLP-1 RAs may inhibit retinal neurodegeneration and reduce proinflammatory processes, which could protect against diabetic retinopathy progression

Tissue culture media supernatants from the final 24 hours of culture were collected and assayed by Amplex Red Glucose/Glucose Oxidase Assay Kit (Life Technologies, Gaithersburg, MD, USA), Lactate Assay kit (Sigma-Aldrich) and Rat Ultrasensitive Insulin ELISA (Mercodia, Uppsala, Sweden) to measure total glucose, lactate and insulin respectively

Its receptor GLP-1R is mainly expressed in islet cells in the pancreas, and is also widely expressed in tissues such as stomach, small intestine, heart, kidney, lung and brain