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Treatment response should be reviewed after approximately 6 months according to NICE guidance, with continuation dependent on clinically meaningful improvements in HbA1c

Walking, cycling, and resistance training help burn calories, build muscle, and improve insulin sensitivity

Some individuals experience persistent hunger, food cravings, weight cycling, and difficulty maintaining weight loss even when BMI falls below 27

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Several small-scale human studies have begun to explore these findings in clinical populations

reduce weight as insulin hormone is promoted while glucagon is restricted