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Lopez-Delgado MI, Morales M, Villanueva-Penacarrillo ML, Malaisse WJ, Valverde I

It reveals patterns such as nighttime snacking or hidden calories in beverages

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We believe that the receptor uses the ER as a bridge to access other cellular organelles, opening exciting possibilities to find new ways to improve diabetes therapies." Professor Alejandra Tomas Catala Department of Metabolism, Digestion and Reproduction The paper, published in Nature Communications, uncovers how the GLP-1 receptor (GLP-1R) forms a specialised signalling hub inside pancreatic -cells that supports healthy mitochondria and boosts insulin secretion

Companies pivoting from volume generics to innovation-backed specialty solutions

The overaccumulation of triacylglycerol and cholesterol in the hepatocytes and the overproduction of reactive oxygen species (ROS) both lead to local inflammatory responses