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Statins are recommended as a first-line therapy for the management of lipid disorders.

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In this Review, the authors discuss neuromodulation therapies in relation to current knowledge of the nerve circuitry, provide insights into possible mechanisms and explore reasons for limited success and how effectiveness might be improved.

Novo and Lilly are using their direct-to-consumer online pharmacies to improve adherence, giving them clearer insight into why patients dont fill or refill prescriptions to offer targeted support

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