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, Kamenecka, T

Efficacy In the original phase 3 randomized trials for obesity, average weight reduction compared to placebo has ranged from 5.3 % to 17.8 % after 5672 weeks (Table 1), with improvements in several obesity-related risks and complications [[13], [14], [15]]

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[DOI] [PubMed] [Google Scholar] 57.Smith C., Woessner M.N., Sim M., Levinger I

Much of the foundational work on rapamycin and aging has been conducted in animal models, and while these studies have yielded encouraging data, translating those findings into human protocols is far from straightforward