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However, retatrutide produces greater weight loss (24-29% vs 15-22%), and greater weight loss correlates with higher telogen effluvium incidence

Supplied as a 5mg lyophilised cake ready for room-temperature reconstitution

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Each dose increase happens at four-week intervals, so reaching the full dose takes about 16 to 20 weeks

These mechanisms enable patients to achieve 10-15% body weight reduction in clinical studies, with many healthcare providers finding that sustained appetite control ultimately delivers improved metabolic health and reduced obesity-related complications