glp-1 cancer reduction Dr SABCS 2025: Can GLP-1s Help

However, over the course of the last few years, Pfizer discontinued danuglipron, lotiglipron, and PF-06954522, the first two due to concerning liver enzyme elevations seen in clinical studies

2018;11(6):e201700357

As it relates to our conversation and I think writ large the whole field, youre hearing a lot, a lot more about different mechanisms

Patients with statin intolerance should first consider evidence-based alternatives like ezetimibe, bempedoic acid, PCSK9 inhibitors, or inclisiran before considering GLP-1 therapy primarily for lipid management

Yu X, Tang H, Huang L, Yang Y, Tian B, and Yu C

The agency is also considering a Risk Evaluation and Mitigation Strategy program that would confirm the drugs potential risks do not outweigh the benefits